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Implementation of carbon capture technology such as direct air capture (DAC) is highly needed for EU's climate neutral target. The crystalline porous solids, metal-organic frameworks (MOFs), have demonstrated excel potential for DAC. We recently developed a layered copper-based MOF with a crystal structure that feature...
This BAG application builds on the development of single particle cryoEM in the Italian Structural Biology community, as in Italy there is no top-end instrument is open to rhe structural biology community. The groups in this application have acquired know-how in cryoEM through international collaborations or by acquiri...
basic medicinePaNmedical and health scienceselectron microscopy
Giel LEMMENS · Maria PIERANTONI · Mei YANG · Peter D LEE · y 11 más
This HOAHub will create a physical and virtual Hub which uses HiP-CT to scan whole human organs with local cellular resolution, producing a “Human Organ Atlas in Health and Disease”. It will bridge clinical imaging (centimetre scale) to molecular modalities (nanometer scale), providing unprecedented insights into our b...
PaNx-ray probeParticles, Nuclei and FieldsMedicine
Christoph SAHLE · KARI RUOTSALAINEN · Michael BAKER · Nathan ALCOCK · y 1 más
In 2021, we reported the first instance of thorium–thorium bonding in a crystalline cluster. This compound has sparked significant interest due to its hotly debated electronic structure, which is predicted by density functional theory to exhibit valence-delocalisation of two 6d electrons over three Th metal centres, le...
Jean Louis HAZEMANN · Maria Del Carmen SANCHEZ · Pilar VALSERA MORENO · Denis TESTEMALE · y 4 más
Arsenic (As) is an indicator for the formation of some of the largest hydrothermal gold (Au) deposits. However, the conditions of extraction of As from magmas and its transport by magmatic volatiles remain poorly understood. Here we will determine the partition coefficients of As between granitic melts and Cl/S-bearing...
PaNEarth Sciencesx-ray probeParticles, Nuclei and Fields
Paul TAFFOREAU · Sébastien RIGOLLET · Jean Francois ADAM · SARVENAZ KESHMIRI · y 5 más
Glioblastoma (GBM) is the most common and aggressive primary brain tumour. Due to the chemoresistance and highly infiltrative growth of GBM, current treatments can only slow the development of the disease. The main limit to the effectiveness of chemotherapies in the brain is their restricted access due to the presence...
PaNmedical and health sciencesclinical medicinex-ray probe
The BAG coordinates work in serial synchrotron crystallography, SSX. We propose to collect low dose ground states on enzymes, ligand complexes, and redox sensitive metallo-proteins, using the fixed target chip or foil sample delivery systems at ID29. For time resolved work, we propose laser activated work as well as mi...
basic medicinePaNmedical and health sciencesx-ray probe
RAPHAEL CLADY · Mikhail KOZHAEV · Olivier UTEZA · Frederic LEROY · y 1 más
The possibility of using light to control complex systems on ultra-short timescales provides a powerful tool to probe fundamental phenomena in solid state physics and is promising for future applications. In this proposal we aim at studying the light-induced strain fields in ferroelectric/ferroelastic GeTe thin films w...
Thomas HASE · Jhao-Rong LIN · Didier WERMEILLE · Richard MORRIS
Generating p- or n- type semiconductors through the introduction of either phosphorus (P) or boron (B) has underpinned the semiconductor industry for decades. As device scaling moves towards 3D structures, it is necessary to increase doping levels by 2 -3 orders of magnitude to several at.%. This comes with new materia...
PaNphysical sciencesx-ray probeParticles, Nuclei and Fields
Zihan SONG · Houyi LIU · ZEYU SUN · Pengcheng ZHU · y 5 más
We recently proposed amorphous Fe-based and V-based high ionic conductivity halide cathode materials, which can cycle at room temperature without the additional catholyte. Both halide cathode materials present multi-electron transfer reactions for lithium storage, as well as rapid ionic transport characteristics. To in...
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