Buscador de Tesis y publicaciones académicas

A new acylated quercetin triglycoside with anti-inflammatory activity from the leaves of <i>Camellia flavida</i> var. <i>flavida</i>

Gui-Xiang Liang · Nan-Yan Liao · Ze-Jia Li · Ke-Di Yang · y 3 más

Phytochemical investigation of the leaves of Camellia flavida var. flavida led to the isolation of a previously undescribed acylated quercetin triglycoside (1), together with three known constituents (2&#x2013;4). Their structures were established by HR-ESI-MS with 1D and 2D NMR analyses and, for the known compounds, b...

Single-cell transcriptomics reveals transcriptional and metabolic alterations associated with disease severity in β-thalassemia/Hb E

Sukhuma, Chanyanat · Thongphayong, Sudarat · Muangtate, Pattaratorn · Wongvises, Pavarisa · y 3 más

Single-cell RNA sequencing was used to analyze transcriptional profiles during erythropoiesis in erythroblasts from normal subjects, mild, and severe β-thalassemia/Hb E patients, revealing disease severity- and differentiation stage-associated alterations in erythroid transcriptional states. Erythroblasts from each gro...

Chemical constituents from the roots of <i>Polygala fallax</i> Hemsl

Ping Luo · Shanhui Yi · Can Liu · Hui Zou

A new oligosaccharide ester, namely 3&#x2032;-O-(Z)-3,4,5-trimethoxy-cinnamoyl-sucrose (1) along with nine known compounds (2&#x2013;10), were isolated from the roots of Polygala fallax Hemsl. The structure of new compound was elucidated using 1D, 2D NMR, and HRESIMS methods. Furthermore, compounds 2&#x2013;10 were iso...

Mode and tempo of social parasite speciation in eusocial wasps

von Adelmannsfelden, Sarah · Gotzek, Dietrich · Härtel, Max Paul · Rabeling, Christian

Co-evolutionary interactions between species are a major driver of diversification. The antagonistic interactions between avian brood parasites and their hosts are textbook examples of co-evolutionary arms races that can result in diversification. The mechanisms of brood parasite speciation of social insects are less w...

Peroneutone A, a new highly oxygenated diterpenoid with diverse biological activities from <i>Peroneutypa scoparia</i>

Dongsheng Ma · Xingyue Lu · Lili Meng · Wenbin Xia · y 3 más

A chemical investigation of the endophytic fungus Peroneutypa scoparia RJHH-3 led to the isolation of a new highly oxygenated pimarane diterpenoid, peroneutone A (1), together with three known analogues, scopararane C (2), libertellenone A (3), and 9&#x03B1;-hydroxyisopimara-8(14),15-dien-7-one (4). The structure of 1...

Refinement of BindCraft Nectin4 Minibinder seeds with Option I and Option II genetic cycle

Hölzel, Michael · Hagelueken, Gregor

This archive contains structural models and sequence datasets from Nectin-4 AI-minibinder design and diversification workflows. It includes BindCraft-generated Nectin-4 seed designs and RFdiffusion-generated Nectin-4 seed designs, together with variants generated by two downstream diversification strategies: partial-di...

Gastroprotective potential of <i>Bixa orellana</i>: A critical review of extract-specific phytochemistry and preclinical evidence

Asma Syuhaily Mohd Yusof · Yong Yoke Keong · Fong Lai Yen · Ng Chin Theng · y 5 más

Peptic ulcer disease remains clinically important despite effective Helicobacter pylori (H. pylori) eradication and acid-suppressive therapy. Gastric injury reflects an imbalance between aggressive factors, including acid-pepsin activity, H. pylori, non-steroidal anti-inflammatory drugs (NSAIDs), ethanol, oxidative str...

Do strategies make a difference? Evaluating the impact on video-based learning and student engagement in K-12 education

Autoría no especificada

Appendix1. Photographs of 269 Plant Taxa Included in a Long-Term Flowering Phenology Dataset from Tokyo, Japan

Tokumoto, Yuji · Yoshino, Yumiko · Endo, Takumi · Katsumata, Chifuyu · y 1 más

This dataset contains photographic reference images for 269 plant taxa monitored at the Institute for Nature Study, National Museum of Nature and Science, Tokyo, Japan. The photographs are provided to support taxonomic identification of taxa included in a long-term flowering phenology dataset collected between 2009 and...

Discovery of a new bioactive Taxifolin <i>α</i>-glycoside from <i>Scorzonera coriacea</i>, antimicrobial activities, cytotoxic effects, and a silico study

Büşra Korkmaz · Sara Çiğdem Malkoç · Gözde Bozdal · Elif Öztürk · y 6 más

In this study, one new compound (1) and eight known compounds (2&#x2013;9) were identified from the aerial parts of endemic Scorzonera coriacea. The chemical structures of the isolated compounds were elucidated using extensive spectroscopic analyses (1D and 2D NMR, FT-IR, UV, and LC-QTOF-MS). The antimicrobial activiti...