Buscador de Tesis y publicaciones académicas

Development and Psychometric Validation of the TF-Col: A Patient- and Caregiver-Reported Measure of Financial Toxicity in Oncology

Julio César, Sánchez-Arévalo · Fabio Alexander, Sierra-Matamoros · Marcela, Pérez Sosa · Diana Isabel, Cuéllar Rivera · y 1 más

To develop and psychometrically validate the TF-Col, a patient- and caregiver-reported outcome measure to assess financial toxicity in adult and pediatric oncology populations in a middle-income Latin American context.A multicenter study following Consensus-based Standards for the Selection of Health Measurement Instru...

Development and Real-World Application of a Consumption-Based Model for Projecting the Budget Impact of High-Cost Reserve Antibiotics in a University Hospital

Martellone, Lorenzo · Servidio, Camilla · Leanza, Cristiana · Tomolillo, Dario · y 6 más

Traditional budget impact analysis models, usually based on predefined populations, often fail to capture the complexity of hospital antibiotic use, which is dynamic and often empirical. To address this gap, we developed and applied an adaptable budget impact analysis model based on real-world consumption data of high-...

Partial Economic Evaluation and Clinical Impact of a Stewardship Quality-Improvement Intervention to Reduce Intravenous Antibiotic Duration: A Quasi-Experimental Study

Harli Pasquini-Netto · Stella Caroline Schenidt Bispo da Silva · Mariana Millan Fachi · Marinei Campos Ricieri · y 8 más

Surgical site and community-acquired osteoarticular infections cause prolonged hospitalization, high costs, and health system burden. Although early intravenous-to-oral (IV-to-PO) antibiotic switch is internationally established, adoption remains limited in Brazil.To evaluate the effectiveness and direct medical costs...

New pulse sequence for improving cardiac black-blood and PSIR MRI quality in cases of arrhythmia

Tan, Huan · Wang, Dong · Li, Yuehua

Most conventional cardiac MRI scans, which rely on electrocardiogram (ECG)-triggered segmented acquisition for k-space data, are highly sensitive to arrhythmia-a vulnerability that can induce severe motion artifacts, thereby degrading image quality and diagnostic accuracy. This study developed a novel pulse sequence: a...

Cost-Utility Analysis of Sentinel Node Biopsy Versus Selective Neck Dissection for Node-Negative Early-Stage Oral Cancers: A Health Economic Evaluation from the Indian Healthcare System Perspective

Krishnakumar, Thankappan · Lakshmi Ravunniarth, Menon · Tejal, Patel · Sujha, Subramanian · y 1 más

To conduct a cost-utility analysis comparing sentinel node biopsy (SNB) with selective neck dissection (SND) for clinically node-negative early-stage oral cancer from the Indian healthcare system perspective.A hybrid decision-tree-Markov model compared SNB with SND over a 10-year horizon, incorporating 18 clinical path...

Cost-Effectiveness Analysis of Asciminib in Patients With Chronic Phase Chronic Myeloid Leukemia Previously Treated With 2 or More Tyrosine Kinase Inhibitors in Colombia

Mateo, Ceballos · Virginia, Abello · Pieralessandro, Lasalvia · Paola, Jaramillo · y 3 más

To assess the cost-effectiveness of asciminib in adult patients with chronic-phase chronic myeloid leukemia who have been treated with 2 or more tyrosine kinase inhibitors, from a third-party payer perspective in Colombia.A nonhomogeneous partitioned survival model was developed using ASCEMBL trial and matching-adjuste...

Language reorganization in brain arteriovenous malformations with fiber-based regional functional connectivity

Qiji Shi · Xiaofeng Deng · Zekun Han · Leqing Zhou · y 3 más

Structure and function changes of language function processing in brain arteriovenous malformations (AVMs) have been investigated, while the alterations of brain connectivity remain unexplored. This study aims to investigate language network reorganization in AVMs using fiber-based regional functional connectivity (FBR...

Probabilistic Sensitivity Analysis of Thalassemia Screening Cascade Efficiency: Single-Sample Versus Multivisit Protocols in Malaysia

Azrin Syahida, Abd Rahim · Safurah, Jaafar · Zukarnain, Zakaria · Don Ismail, Mohamed · y 1 más

Malaysia's National Thalassemia Screening Program uses multivisit sequential testing (protocol 1), with a dropout rate of 20%, disproportionately affecting rural and underserved populations in Sabah and Sarawak. Protocol 2 proposes 3-tier testing from a single retained blood sample, eliminating visit-based dropout. Pre...

Cost-Effectiveness Analysis of Fecal Immunochemical Test-based Versus Total Colonoscopy-Based Colorectal Cancer Screening in Japan: A Microsimulation Study

Taichi, Mori · Nobuyuki, Shimohata · Rei, Goto

Colorectal cancer is a major public health concern with a high mortality rate. Fecal immunochemical tests (FIT) and total colonoscopy (TCS) are recommended screening methods; however, their cost-effectiveness varies by country. This study addressed the lack of comprehensive cost-effectiveness analyses comparing TCS wit...

Carboniferous 2: Rise of plant community complexity and climate interaction

Gurung, K. · Xu, Z. · Dutton, J. · Zheng, D. · y 1 más