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148.415.802 resultados

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Artículo 2027 Acceso abierto Revisado por pares

High-sensitivity quantification of angiotensin oligopeptides using methoxyacetylation coupled with LC-TIMS-qTOF/MS

Xiaoqi Yang · Jueri Kawada · Tadashi Hayama · Toshiro Matsui

Quantification of key effectors in the circulating renin-angiotensin system (RAS), including angiotensin (Ang) I, Ang (1-9), Ang II, Ang (1-7), and Ang A, is essential for understanding RAS-mediated blood pressure regulation. Herein, we present a highly sensitive and selective analytical method based on methoxyacetylat...

health sciences medical and health sciences
  • Elsevier BV
  • English
  • DOI: 10.1016/j.talanta.2026.130507
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Artículo 2027 Acceso abierto Revisado por pares

Establishment of the heart cytoarchitecture: A histological, immunohistochemical, and ultrastructural study in goats (Capra hircus)

Fatma El-Zahraa A. Mustafa · Hanan H. Abd-Elhafeez · Catrin Sian Rutland · Soha A. Soliman

Goat products carry economic importance worldwide yet relatively little is published about the cardiovascular structure and function in this important animal. Goat hearts have played essential roles as models for human cardiovascular diseases and in artificial heart studies. The present study investigated key structura...

  • Elsevier BV
  • English
  • DOI: 10.1016/j.tice.2026.103890
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Artículo 2027 Acceso abierto Revisado por pares

Assessing the applicability of existing design recommendations to AI companion design: A multi-method study

Soobin Cho · Deveshi Modi · Divya Mavinkurve · Jieqiong Ding · y 1 más

With the rapid proliferation of large language model (LLM)-based systems, AI companions have emerged as conversational agents designed to cultivate emotional connection rather than primarily to support humans in instrumental tasks. Because engagement with AI companions involves relational, emotional, and potentially lo...

Human-Computer Interaction Artificial Intelligence
  • Elsevier BV
  • English
  • DOI: 10.1016/j.ijhcs.2026.103940
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Artículo 2027 Acceso abierto Revisado por pares

Shipi Zengye formula simultaneously ameliorates functional constipation and depression by upregulating SLC6A3 and remodeling the Prevotella copri–bile acid axis

Ling, Yao · Zi-Qi, Tang · Xiang-Yi, Bu · Yu-Fei, Li · y 5 más

Functional constipation (FC) and depression frequently coexist, yet the gut-brain mechanisms underlying this comorbidity remain poorly understood. Shipi Zengye Formula (SPZY), a traditional Chinese medicine (TCM) formula, is clinically used to treat constipation accompanied by depressive symptoms; however, its therapeu...

basic medicine medical and health sciences
  • Elsevier BV
  • English
  • DOI: 10.1016/j.jep.2026.122302
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Artículo 2027 Acceso abierto Revisado por pares

Machine learning-enabled large-scale capacity expansion planning under uncertainty

Taehyeon Kwon · Anirudh Subramanyam

Capacity expansion planning under uncertainty requires selecting a scenario count and representative operational horizon to estimate average production costs. Small choices risk unreliable plans, while large choices become intractable. We propose AutoSCEP, an automated, statistically grounded procedure that, for a fixe...

Optimization and Control (math.OC) Optimization and Control FOS: Mathematics engineering and technology
  • Elsevier BV
  • English
  • DOI: 10.1016/j.epsr.2026.113791
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Artículo 2027 Acceso abierto Revisado por pares

Demonstrating oxy-fuel combustion of pulverized forest residues in a down-fired furnace with external flue gas recirculation

Florian M. Schmidt · Emil Thorin · Henrik Wiinikka · Markus Carlborg · y 1 más

Solid biomass oxy-fuel combustion with external recirculation was demonstrated in a 100-kW atmospheric, down-fired combustor operated close to stoichiometry. The external recirculation setup comprised a particulate filter, a condenser, a fan and O2 addition before the burner inlet. A theoretical description of the reci...

Solid biomass Atom and Molecular Physics and Optics Energy Engineering engineering and technology
  • Elsevier BV
  • Sweden
  • English
  • DOI: 10.1016/j.fuel.2026.140753
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Artículo 2027 Acceso abierto Revisado por pares

A new species of Hepatozoon Miller, 1908 (Apicomplexa: Hepatozoidae) parasitizing Philodryas nattereri (Squamata: Dipsadidae) from the Caatinga, Brazil

Carla Adrielle Costa de, Carvalho · Gabriela, Felix-Nascimento · Fabiano Matos, Vieira · Antônio Carlos Santos, Ferreira · y 4 más

Brazil has a rich snake fauna with 435 species, 112 of which occur in the Caatinga biome. The genus Hepatozoon comprises over 300 species, with 40 described in Brazilian snakes. The objective of this study was to characterize morphologically and molecularly a undescribed species of Hepatozoon that infects Philodryas na...

health sciences medical and health sciences Liver Eucoccidiida
  • Elsevier BV
  • English
  • DOI: 10.1016/j.parint.2026.103360
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Artículo 2027 Acceso abierto Revisado por pares

Bijections and congruences involving lattice paths and integer compositions

Manosij Ghosh Dastidar · Michael Wallner

We prove new bijections between different variants of Dyck paths and integer compositions, which give combinatorial explanations of their simple counting formula $4^{n-1}$. These give relations between different statistics, such as the number of crossings of the $x$-axis in classes of Dyck bridges or the distribution o...

05A19, 05A15, 05A17 Combinatorics Number Theory FOS: Mathematics
  • Elsevier BV
  • English
  • DOI: 10.1016/j.disc.2026.115389
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Artículo 2027 Acceso abierto Revisado por pares

Real-time NMR analysis of glutamine metabolism for screening anti-cancer agents in living cells

Lei, Yating · Huang, Tao · Chai, Xin · Fan, Xinyu · y 4 más

Metabolic reprogramming is a substantial obstacle for anticancer drug screening, as targeted therapeutics often lose efficiency due to the dynamic adaption of cancer cells. Glutamine metabolism in cancer profoundly impacts tumor initiation, progression and metastasis. The existing agents are compromised by resistance a...

health sciences medical and health sciences Research Article
  • Elsevier BV
  • English
  • DOI: 10.1016/j.mrl.2026.200293
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Artículo 2027 Acceso abierto Revisado por pares

Investigating the disappearance of a type-C QPO in black hole X-ray binary Swift J151857-572147 with AstroSat

Biki Ram · Manoneeta Chakraborty · Mayukh Pahari

We present a timing and broadband spectral study of the AstroSat observation of the black hole low mass X-ray binary Swift J151857.0--572147, focusing on its evolution across two temporal segments, S1 and S2. During the first segment S1 lasting $\sim$ 50.6 ks, the source shows a clear type-C QPO at $\sim8.02$ Hz and a...

High Energy Astrophysical Phenomena (astro-ph.HE) FOS: Physical sciences High Energy Astrophysical Phenomena
  • Elsevier BV
  • English
  • DOI: 10.1016/j.jheap.2026.100738
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Resultados provistos por OpenAIRE, la infraestructura europea de ciencia abierta. Tesis y Másters Colombia no aloja ni distribuye estos documentos: cada enlace lleva al repositorio de origen.

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