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Quantification of key effectors in the circulating renin-angiotensin system (RAS), including angiotensin (Ang) I, Ang (1-9), Ang II, Ang (1-7), and Ang A, is essential for understanding RAS-mediated blood pressure regulation. Herein, we present a highly sensitive and selective analytical method based on methoxyacetylat...
Fatma El-Zahraa A. Mustafa · Hanan H. Abd-Elhafeez · Catrin Sian Rutland · Soha A. Soliman
Goat products carry economic importance worldwide yet relatively little is published about the cardiovascular structure and function in this important animal. Goat hearts have played essential roles as models for human cardiovascular diseases and in artificial heart studies. The present study investigated key structura...
Soobin Cho · Deveshi Modi · Divya Mavinkurve · Jieqiong Ding · y 1 más
With the rapid proliferation of large language model (LLM)-based systems, AI companions have emerged as conversational agents designed to cultivate emotional connection rather than primarily to support humans in instrumental tasks. Because engagement with AI companions involves relational, emotional, and potentially lo...
Ling, Yao · Zi-Qi, Tang · Xiang-Yi, Bu · Yu-Fei, Li · y 5 más
Functional constipation (FC) and depression frequently coexist, yet the gut-brain mechanisms underlying this comorbidity remain poorly understood. Shipi Zengye Formula (SPZY), a traditional Chinese medicine (TCM) formula, is clinically used to treat constipation accompanied by depressive symptoms; however, its therapeu...
Capacity expansion planning under uncertainty requires selecting a scenario count and representative operational horizon to estimate average production costs. Small choices risk unreliable plans, while large choices become intractable. We propose AutoSCEP, an automated, statistically grounded procedure that, for a fixe...
Optimization and Control (math.OC)Optimization and ControlFOS: Mathematicsengineering and technology
Florian M. Schmidt · Emil Thorin · Henrik Wiinikka · Markus Carlborg · y 1 más
Solid biomass oxy-fuel combustion with external recirculation was demonstrated in a 100-kW atmospheric, down-fired combustor operated close to stoichiometry. The external recirculation setup comprised a particulate filter, a condenser, a fan and O2 addition before the burner inlet. A theoretical description of the reci...
Solid biomassAtom and Molecular Physics and OpticsEnergy Engineeringengineering and technology
Carla Adrielle Costa de, Carvalho · Gabriela, Felix-Nascimento · Fabiano Matos, Vieira · Antônio Carlos Santos, Ferreira · y 4 más
Brazil has a rich snake fauna with 435 species, 112 of which occur in the Caatinga biome. The genus Hepatozoon comprises over 300 species, with 40 described in Brazilian snakes. The objective of this study was to characterize morphologically and molecularly a undescribed species of Hepatozoon that infects Philodryas na...
health sciencesmedical and health sciencesLiverEucoccidiida
We prove new bijections between different variants of Dyck paths and integer compositions, which give combinatorial explanations of their simple counting formula $4^{n-1}$. These give relations between different statistics, such as the number of crossings of the $x$-axis in classes of Dyck bridges or the distribution o...
Lei, Yating · Huang, Tao · Chai, Xin · Fan, Xinyu · y 4 más
Metabolic reprogramming is a substantial obstacle for anticancer drug screening, as targeted therapeutics often lose efficiency due to the dynamic adaption of cancer cells. Glutamine metabolism in cancer profoundly impacts tumor initiation, progression and metastasis. The existing agents are compromised by resistance a...
health sciencesmedical and health sciencesResearch Article
We present a timing and broadband spectral study of the AstroSat observation of the black hole low mass X-ray binary Swift J151857.0--572147, focusing on its evolution across two temporal segments, S1 and S2. During the first segment S1 lasting $\sim$ 50.6 ks, the source shows a clear type-C QPO at $\sim8.02$ Hz and a...
High Energy Astrophysical Phenomena (astro-ph.HE)FOS: Physical sciencesHigh Energy Astrophysical Phenomena
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