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148.399.619 resultados

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Artículo 2027 Acceso abierto Revisado por pares

Improved catalytic efficiency of P450 OleP for converting lithocholic acid into murideoxycholic and ursodeoxycholic acids through semi-rational and rational design

Baodong Hu · Cuiping Pang · Ding Luo · Yongchao Wang · y 8 más

Cytochrome P450 enzymes are promising for synthesizing therapeutically beneficial bile acids murideoxycholic acid (MDCA) and ursodeoxycholic acid (UDCA) from lithocholic acid (LCA). However, the catalytic efficiency of P450 enzymes remains inadequate for large-scale production. Here, we address this limitation by engin...

Original Research Article natural sciences chemical sciences
  • Elsevier BV
  • English
  • DOI: 10.1016/j.synbio.2026.05.015
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Artículo 2027 Acceso abierto Revisado por pares

Coherent structures and bifurcation analysis in a toxin-driven plant–herbivore model

Grifó Gabriele · Valenti Giovanna

This work investigates how toxin-mediated interactions and directed movements shape the emergence of coherent structures in plant-herbivore systems. The analysis focuses on a two-compartment model enclosing a toxin-dependent functional response and a cross-diffusion term that represents ecologically plausible herbivore...

biological sciences FOS: Mathematics FOS: Physical sciences Mathematical Physics (math-ph)
  • Elsevier BV
  • English
  • DOI: 10.1016/j.matcom.2026.07.048
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Artículo 2027 Acceso abierto Revisado por pares

Proving the existence of localized patterns, periodic solutions, and branches of periodic solutions in the 1D Thomas model

Blanco, Dominic

In this paper, we present a general framework for constructively proving the existence of stationary localized solutions, spatially periodic solutions, and branches of spatially periodic solutions in the 1D Thomas model. Specifically, we develop the necessary analysis to compute explicit upper bounds required in a Newt...

Numerical Analysis Analysis of PDEs FOS: Mathematics Numerical Analysis (math.NA)
  • Elsevier BV
  • English
  • DOI: 10.1016/j.matcom.2026.08.004
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Artículo 2027 Acceso abierto Revisado por pares

Self-supervised graph neural networks for optimal substation reconfiguration

Antoine Martinez · Balthazar Donon · Louis Wehenkel · Efthymios Karangelos

Changing the transmission system topology is an efficient and costless lever to reduce congestion or increase exchange capacities. The problem of finding the optimal switch states within substations is called Optimal Substation Reconfiguration (OSR), and may be framed as a Mixed Integer Linear Program (MILP). Current s...

engineering and technology Systems and Control (eess.SY) Systems and Control
  • Elsevier BV
  • English
  • DOI: 10.1016/j.epsr.2026.113609
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Artículo 2027 Acceso abierto Revisado por pares

Output-feedback adaptive model predictive control for ramp metering: A set-membership approach

Li, Zhexian · Savla, Ketan

Ramp metering, which regulates the flow entering the freeway, is one of the most effective freeway traffic control methods. This paper introduces an output-feedback adaptive approach to ramp metering that combines model predictive control (MPC) with set-membership parameter and state estimation. The set-membership esti...

mechanical engineering engineering and technology Systems and Control (eess.SY) Systems and Control
  • Elsevier BV
  • English
  • DOI: 10.1016/j.automatica.2026.113290
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Conjunto de datos 2027 Acceso abierto

PROTEINS RELATED TO PATHOGENESIS OF DISEASES, VIRAL PROTEINS, CELL DIVISION, SIGNALLING AND CHROMATIN PROCESSES

Lorenzo BASILE · Marco MALATESTA · Max NANAO · Federico FORNERIS

The outstanding research questions of our BAG focus on proteins and their complexes involved in a variety of processes, ranging from cell homeostasis (from gene regulation to folding quality control, from energy metabolism to signal transduction) to communication and surface recognition (including trans-interactions be...

basic medicine PaN medical and health sciences ID23-2
  • ESRF (European Synchrotron Radiation Facility...
  • English
  • DOI: 10.15151/esrf-es-1471245503
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Artículo 2027 Acceso abierto Revisado por pares

HA1-T138A and HA1-Q226L substitutions in H3N2 canine influenza virus contribute to binding to human-type α2,6-linked sialic acid receptors

Wataru, Sekine · Haruhiko, Kamiki · Hiroho, Ishida · Hiromichi, Matsugo · y 7 más

The H3N2 canine influenza A virus (IAV), which originated from an H3N2 avian IAV, has caused outbreaks in North America and Asia. Although H3N2 canine IAV has not been reported to transmit to humans, understanding the molecular basis of receptor tropism changes is important for viral surveillance and zoonotic risk asse...

  • Elsevier BV
  • English
  • DOI: 10.1016/j.virol.2026.111071
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Conjunto de datos 2027 Acceso abierto

Detemination of the spin and orbital moment of the photomagnetic octacyanotungstate(IV) in high-temperature photomagnets

Nathan YUTRONKIE · Michal MAGOTT · Gabriela HANDZLIK · Katarzyna RZEPKA · y 1 más

Coordination polymers based on octacyanotungstate(IV) and magnetically non-innocent manganese(II) complex cations establish a new class of high-temperature photomagnets with photo-induced magnetic ordering temperatures exceeding the boiling point of liquid nitrogen. In this proposal we aim to fully determine the mechan...

PaN Chemistry ID12 Particles, Nuclei and Fields
  • ESRF (European Synchrotron Radiation Facility...
  • English
  • DOI: 10.15151/esrf-es-1437867929
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Artículo 2027 Acceso abierto Revisado por pares

On putative self-similarity for incompressible 3D Euler

Constantin, Peter · Ignatova, Mihaela · Vicol, Vlad

We consider hypothetical solutions of 3D Euler which blow up in finite time in a self-similar fashion. We prove that if the initial data has finite kinetic energy, then the similarity exponent $γ$ which governs the rate of zooming in must be at least $2/5$. If a smooth globally self-similar blowup profile exists, and t...

physical sciences Analysis of PDEs FOS: Mathematics natural sciences
  • Mathematical Sciences Publishers
  • English
  • DOI: 10.2140/courant.2027.1.1
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Resultados provistos por OpenAIRE, la infraestructura europea de ciencia abierta. Tesis y Másters Colombia no aloja ni distribuye estos documentos: cada enlace lleva al repositorio de origen.

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