Buscador de Tesis y publicaciones académicas

Tesis doctoral 2028

Novel encapsulation of biofilm-enriched black carbon for polychlorinated biphenyl bioremediation

Dong, Qin

Polychlorinated biphenyls (PCBs) were banned from manufacture in 1979 but persist in the environment and strongly bind to sediments. Lower chlorinated PCBs (LC-PCBs), defined as four or less chlorines per PCB and the most volatile PCBs, more easily transport from sediment into the air than higher chlorinated PCBs. Expo...

Sol-Gel environmental biotechnology Biodegradation Biphenyl Dioxygenase Gene Expression

• The University of Iowa
• English
• DOI: 10.25820/etd.008157

Ver ficha

Tesis doctoral 2028

Natural and artificial grottoes in ancient Roman villas

Aung, Myat Thinzar

This dissertation contextualizes the sensory designs of natural and artificial caves with hydraulic features that were embedded into Roman villas in Italy from the second century BCE to the second century CE. These grottoes were decorated with architectural elements, stuccoes, mosaics, paintings, and/or sculptures that...

11. Sustainability 8. Economic growth history and archaeology humanities and the arts

• The University of Iowa
• English
• DOI: 10.25820/etd.007403

Ver ficha

Tesis doctoral 2028

Novel roles for heat shock factor 1 (HSF1) in gene expression in Caenorhabditis elegans

Min, Sehee

Maintaining cellular homeostasis through adaptive responses to external stimuli is fundamental to survival. While the Heat Shock Response (HSR) is often characterized by dramatic transcriptional shifts, it also requires precise regulatory control to ensure cellular integrity. HSF-1 (Heat Shock Factor 1) serves as the m...

• The University of Iowa
• English
• DOI: 10.25820/etd.008533

Ver ficha

Tesis doctoral 2028

Sanctuary, shelters, and the state

Ruiz Martinez, Carlos

In the 1980s, religious communities in the US-Mexico borderlands offered refuge to Central American migrants fleeing civil conflicts and repressive regimes and entering the United States irregularly, or without lawful permission. This became known as the sanctuary movement. Sanctuary activists argued that their religio...

sanctuary movement liberation theology Cold War migrant shelters

• The University of Iowa
• English
• DOI: 10.25820/etd.008476

Ver ficha

Tesis doctoral 2028

ApoE4 − a genetic risk factor for Alzheimer’s disease and its association with hypertension

Shahab, Nusaira Beenta

Alzheimer’s disease (AD) is the most common cause of dementia in older adults and represents a rapidly escalating global health challenge. AD is characterized by the presence of amyloid-β (Aβ) plaques and neurofibrillary tangles (NFT) composed of hyperphosphorylated tau (pTau). Among the genetic determinants, the ε4 al...

Apolipoprotein E4 Hypertension Neurosciences Apolipoprotein E

• The University of Iowa
• English
• DOI: 10.25820/etd.008452

Ver ficha

Tesis doctoral 2028

Impact of target-mediated drug disposition (TMDD) for small molecules in drug discovery and drug development

Xu, Min

Target-mediated drug disposition (TMDD) is generally described as a pharmacokinetic (PK) phenomenon in which drug disposition is significantly influenced by a substantial fraction of drug molecules (relative to the administered dose) binding to a high-affinity and low-capacity pharmacological target. TMDD can occur in...

medical and health sciences clinical medicine Minimal physiologically-based pharmacokinetic (mPBPK) model Pharmacokinetics (PK)

• The University of Iowa
• English
• DOI: 10.25820/etd.008320

Ver ficha

Tesis doctoral 2028

FABRICATING IDENTITIES

Dhawan, Kanupriya

This dissertation examines how South Asian women in Portland, USA, negotiate cultural identity through clothing. I introduce the term ‘Strategic Sartorial Essentialism’ to describe how women selectively express their desi identity in response to occasion, audience and perceived risk. Findings from participant observati...

Material Culture Everyday Clothing Choices Ethnography Gender studies

• Washington State University
• English
• DOI: 10.7273/000008396

Ver ficha

Tesis doctoral 2028

Understanding the physiological functions of circMbl and MBL in Drosophila melanogaster

Krishnamoorthy, Aishwarya

Circular RNAs (circRNAs) are a class of RNA molecule formed by a process called backsplicing, where a downstream splice-site joins with an upstream splice-site forming a covalently closed loop structure. CircRNAs are highly expressed and evolutionarily conserved across species. The gene locus of muscleblind (mbl) under...

basic medicine medical and health sciences

• English
• DOI: 10.48617/etd.664

Ver ficha

Tesis doctoral 2028

EXAMINATION OF PLANT PROTEINS AND THEIR BEHAVIOUR DURING TWIN SCREW EXTRUSION

Bernin, Joshua Brandon

The consumption of plant-based meat analogs has been on the rise in the last decade due to their nutritional value, sustainability, and necessity to meet global protein demands. However, the production of plant-based meat analogs produced using twin-screw extrusion and the main mechanisms of texturization are yet to be...

agricultural biotechnology Extrusion Texturization Protein

• Washington State University
• English
• DOI: 10.7273/000008408

Ver ficha

Tesis doctoral 2028

Cellular and molecular consequences of genetic variants in inherited retinal disease

Mullin, Nathaniel K

Finally, Chapters 6 and 7 focus on a peculiar genetic system found within human cells, the mitochondrial genome (mtDNA). Mitochondria are semi-autonomous organelles that possess a small, high copy-number genome that encodes only 13 protein-coding genes yet is essential to life. Variants on the mtDNA are known to cause...

health sciences medical and health sciences

• The University of Iowa
• English
• DOI: 10.25820/etd.008412

Ver ficha