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The skin is the largest organ of the human body and the first line of defence against external factors, yet extensive skin defects pose a major challenge in reconstructive surgery. Traditional reconstructive methods, such as skin grafts and local or free flaps, are limited by donor site morbidity and the risk of compli...
Hearing loss is common in childhood and, depending on the etiology, affects different ages, from newborns to school-age children. Given the multiple etiologies and diverse clinical presentation, the diagnostic process is difficult and often prolonged. Hearing loss in newborns and younger children negatively affects lan...
Malignancies are one of the leading public health concerns of modern society and rank among the most common causes of death worldwide and in the Republic of Croatia. Successful treatment and survival prognosis largely depend on the stage of the disease at the time of diagnosis. National screening programs are based on...
mammographyradiologijamamografijaKliničke medicinske znanosti
Type 2 diabetes mellitus is the most common metabolic disease characterized by insulin resistance in combination with impaired pancreatic beta-cell function, leading to a relative deficiency of insulin. In the early stages of the disease, hyperinsulinemia occurs; however, progressive exhaustion of pancreatic beta cells...
health sciencestype 2 diabetes mellitusinterna medicinaSGLT-2 inhibitors
IgA nefropatija (IgAN) najčešći je od svih primarnih glomerulonefritisa s većom incidencijom među muškarcima u odnosu na žene. Klinička slika bolesti je varijabilna, s bolesnicima koji mogu imati abnormalne nalaze urina, pokazivati simptome i znakove sinfaringitične makroskopske hematurije, RPGN-a, nefritičkog sindroma...
Borderline personality disorder (BPD) is a complex psychiatric disorder characterized by affective and mood instability, impulsivity, identity disturbance and difficulties in interpersonal relationships. Although psychotic symptoms have traditionally been considered transient and stress-induced phenomena within this di...
Vitamin B₁₂ (cobalamin) is an essential cofactor, particularly important in DNA synthesis and the metabolism of fatty acids and amino acids. Inherited disorders of cobalamin transport and metabolism are rare genetic conditions that most commonly present during childhood, especially in infancy. Inherited transport disor...
Kliničke medicinske znanostisindromi malapsorpcijeBiomedicina i zdravstvoClinical Medical Sciences
Obesity represents one of the greatest public health challenges of today and is associated with numerous metabolic, cardiovascular, and pharmacological changes. In addition to increasing the risk of developing chronic diseases, obesity significantly affects the pharmacokinetics and pharmacodynamics of drugs. Changes in...
klinička farmakologija s toksikologijomobesityClinical Pharmacology and Toxicologyfarmakokinetika
Antithrombotic agents are commonly prescribed drugs and they play an important role in prevention and treatment of thromboembolic incidents. Antithrombotic agents include antiplatelet drugs, such as acetylsalicylic acid and P2Y12 inhibitors and anticoagulant agents, such as vitamin K antagonists, direct oral anticoagul...
Hormonal contraception is one of the most significant methods of pregnancy prevention and, in addition to its primary contraceptive effect, provides numerous non-contraceptive benefits. The literature frequently mentions a reduced incidence of ovarian and endometrial cancer associated with the use of hormonal contracep...
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