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Tesis doctoral 2027

Cancer risk informed by Mendelian genetics

Nielsen Dandoroff, Emily Claire

Height is a well-established risk factor for cancer development, with each 10cm increase in height correlating to a ~10% increase in cancer risk. There does not appear to be a simple explanation for this association, reflecting the genetic complexities of both height and cancer. Mendelian (single gene) syndromes have t...

UK Biobank Variant deleteriousness predictors Growth deficiency syndromes Meier-Gorlin syndrome
  • University of Otago
  • English
  • DOI: 10.82348/our-archive.00352
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Tesis doctoral 2027

Context-aware classification of static analysis warnings guided by coding standards using machine learning and large language models

Kiyaduwa Vithanage, Lakmal Deshapriya

The software industry is continuously growing, and software source code quality is becoming more critical than ever. As a result, methodologies for software validation and verification are being developed, including Static Code Analysis (SCA) tools. SCA tools generate warnings for potential code quality violations, and...

Machine Learning Large Language Models Static Code Analysis Tools Context-aware Classification
  • University of Otago
  • English
  • DOI: 10.82348/our-archive.00398
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Tesis doctoral 2027

Raman spectroscopy for biomedical applications

Chalmers, Mitchell Clemance

Breast cancer remains a major global health burden, and microcalcifications are an important feature frequently seen on mammograms. These microcalcifications occur in two distinct chemical forms, calcium oxalate and hydroxyapatite. However, only hydroxyapatite is potentially associated with malignancy. Conventional mam...

Machine Learning Raman spectroscopy Breast Microcalcifications
  • University of Otago
  • English
  • DOI: 10.82348/our-archive.00267
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Tesis doctoral 2027

Pounamu in the shaping: An archaeology of specialised jade manufacture in the South Island, New Zealand. Ko te whakairo pounamu: Te mātai whaipara tangata o te mahi to tohunga ki te Waipounamu, Aotearoa

Mauger, Anne-Claire Valérie Julie

In Aotearoa New Zealand, pounamu (jade) remains the most significant taonga (treasure) for Māori, embodying mana (prestige), tradition and spirituality. During the late 19th century, a substantial number of pounamu artefacts were fossicked from archaeological sites, resulting in the loss of their original context and d...

craft complexity jade oiling experimental
  • University of Otago
  • English
  • DOI: 10.82348/our-archive.00230
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Tesis doctoral 2027

Innate immune and inflammatory responses to coronaviruses

Lowery, Shea A.

SARS-CoV-2 also encodes many innate immune antagonist genes and is excellent at subverting the host immune response. Immune dysregulation leads to the development of both acute disease, as well as long term disease manifestations called post-acute sequelae of SARS-CoV-2 (PASC). To develop effective therapeutics for pat...

basic medicine medical and health sciences Coronaviruses COVID-19
  • English
  • DOI: 10.25820/etd.007742
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Tesis doctoral 2027

Interfacing Superconducting Qubits with Light

Chiappina, Piero

Superconducting quantum circuits are a leading hardware candidate for realizing a large-scale fault-tolerant quantum computer. However, scaling superconducting quantum computers will soon approach the physical limits imposed by their cryogenic operating environments. Consequently, interconnects between multiple process...

Physics
  • California Institute of Technology
  • English
  • DOI: 10.7907/e5cb-pr72
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Tesis doctoral 2027

EXAMINATION OF BUCKWHEAT AND PROSO MILLET AS EMERGING GRAINS, FOR THEIR PHYSICOCHEMICAL PROPERTIES, PROTEIN, AND END USER APPLICATIONS

Murray-Nalbandian, Elizabeth

The consumption of alternative grains has been on the rise in the last couple of years due to their nutritional value, allergen-friendly properties, and sustainability. However, these crops are unable to match wheat flour functionality. Therefore, this dissertation attempts to understand which buckwheat and proso mille...

emerging grains alternative grains agricultural biotechnology Proso millet
  • Washington State University
  • English
  • DOI: 10.7273/000007892
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Tesis doctoral 2027

Integration of self-cooling photobioreactors into the building envelope

Mirabbasi, Amin

Building on this conceptual framing, the thesis investigates heat-flow and thermal performance through laboratory tests, Design Builder simulations, and field experiments. Laboratory studies isolate the effects of aeration, pigmentation, and water depth on thermal behaviour, demonstrating that aeration suppresses strat...

  • Murdoch University
  • DOI: 10.60867/00000112
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Tesis doctoral 2027

Variable-Density Self-Similar Rayleigh-Taylor Turbulence, and the Path to Get There

Goh, Chian Yeh

The Rayleigh-Taylor (RT) instability arises when a denser fluid is accelerated into a lighter fluid, which eventually transitions into a buoyancy-driven turbulent mixing layer. At sufficiently late times, simple dimensional arguments predict that the mixing-layer height grows self-similarly and quadratically with time....

Turbulence Mechanical Engineering direct numerical simulation Rayleigh-Taylor instability
  • California Institute of Technology
  • English
  • DOI: 10.7907/txqb-x288
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Tesis doctoral 2027

trans-Banglene as a neurotrophic agent

Wijesiri Gunawardana, Piyumi

Proteomic analysis revealed that, rather than directly interacting with the NGF/TrkA pathway, t-BG treatment significantly altered the expression of proteins associated with iron binding and regulation. These findings suggest that t-BG’s biological activity may be linked to iron homeostasis rather than classical neurot...

basic medicine medical and health sciences
  • English
  • DOI: 10.25820/etd.007815
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Resultados provistos por OpenAIRE, la infraestructura europea de ciencia abierta. Tesis y Másters Colombia no aloja ni distribuye estos documentos: cada enlace lleva al repositorio de origen.

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