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The cardiac voltage-gated sodium channel NaV1.5, encoded by SCN5A, is essential for proper cardiac conduction and its dysfunction is implicated in arrhythmias and heart failure. Through careful examination of bioinformatic and genomic data, this dissertation explores previously unrecognized regulatory mechanisms contro...
FOS: Computer and information scienceshealth sciencesmedical and health sciencesBioinformatics
The final part of this thesis presents a systematic benchmark of hybrid transition state search workflows combining six freely available potentials (MACE-OMol25, UMA-Small, UMA-
By combining these theoretical frameworks with the findings of social research conducted in The Philippines and Kuwait, this investigation contributes new insights into the neocolonial societies and subjectivities of exclusion of its key and secondary characters. Through a close reading of Josephine, a Filipina whose d...
Foucaultsocial sciencessocial and economic geographypostcolonial
This thesis first reviews the status of infectious agent knowledge in wild native rodents in Australia, documenting biases in current knowledge that limit the applicability of existing information to native rodent conservation. A two-and-a-half-year study then assesses the baseline health status of extant rodent popula...
veterinary scienceagricultural and veterinary sciences
Over four chapters, I perform analyses of paratexts (physical merchandise, promotional material, and social media platforms) aimed at cinephiles and conduct interviews with individual cinephiles to uncover their evolving relationship with these media industries. Chapter One investigates how boutique labels such as the...
media and communicationscommodificationsocial sciencesmedia convergence
Low temperature stress is one of the most influential environmental factors limiting crop production worldwide. Phenotypic variation in sweet cherry (Prunus avium L.) cold tolerance provides key insights for cultivar selection and breeding. Using a multi-trait approach, along with transcriptomic and genomic analyses, t...
Estuarine ecosystems are hotspots for biogeochemical cycling yet are increasingly threatened by multiple anthropogenic stressors. Among these stressors, microplastic pollution and nitrogen enrichment are known to affect ecosystem functioning individually, but there is a paucity of research on their cumulative impacts....
Social decision-making spans direct interpersonal coordination and large-scale collective dynamics. In dyads, individuals must infer others’ preferences, beliefs, and goals while adjusting their own behavior in real time. In larger social networks, local interactions can accumulate into group-level outcomes such as her...
drift-diffusion modelsreinforcement learningsocial sciencesSocial and Decision Neuroscience
<strong>Introduction</strong>The post-intensive care syndrome involves long-term physical, cognitive, and psychological impairments commonly seen after critical illness. There is limited evidence from Aotearoa/New Zealand on the prevalence and lived experience of PICS, unmet needs, or barriers to recovery. These studie...
medical and health sciencesclinical medicineDisabilityRecovery
Humans and nonhuman animals can quickly identify the number of items in a set, which is vital for adaptation and survival as it enhances the organisms’ ability to collect food, navigate their environment, and assess social interactions, among other situations. This ability relies on nonsymbolic representations of numbe...
Comparative cognitionsocial sciencesDiscriminationpsychology and cognitive sciences
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