Buscador de Tesis y publicaciones académicas

Reduced FOXP3 expression and its association with genetic ancestry in neuromyelitis Optica spectrum disorder: a Colombian cohort

Juliana Lago · Diana M. Narvaéz · Sara Valentina Villanueva · Jairo Gaitán · y 7 más

Autoimmune disorders are characterized by impaired immune tolerance, largely mediated by CD4⁺ regulatory T cells (Tregs), whose function depends on the transcription factor FOXP3.To compare FOXP3 expression levels between patients with neuromyelitis optica spectrum disorder (NMOSD) and healthy controls from Bogotá, Col...

Fixation strength of anterior tibial tuberosity osteotomy in revision knee arthroplasty according to cerclage wire configuration: An experimental animal model

Jhonatan, Males · Juan Pablo, Gómez-Aux · Paul, Stangl-Correa · Willy, Stangl-Herrera · y 2 más

An anterior tibial tuberosity osteotomy (ATTO) is an effective technique to achieve adequate exposure and visualization of the knee joint during revision total knee arthroplasty (TKA). However, various fixation methods have been described once the osteotomy has fulfilled its purpose, with horizontal wire cerclage being...

Associations between dopaminergic and serotonergic systems in individuals with cocaine use disorder: An exploratory analysis of [¹¹C]PHNO and [¹¹C]P943 PET imaging

Salih Cayir · Binah baht Ysrayl · Esteban Sotomayor-Carreño · Alfredo J. Hurtado · y 5 más

[¹ ¹C]PHNO is a positron emission tomography (PET) radioligand for dopamine D2/D3 receptors (D2R/D3R), while [¹ ¹C]P943 selectively targets 5-HT1B receptors. Although prior studies have shown differences in dopaminergic and serotonergic receptor availability in people with and without cocaine use disorder (CUD), these...

A centered Newton method for nonlinear complementarity problem

F. Arenas · R. Pérez · M. Gonzalez-Lima · C.A. Arias

Socioeconomic and sociodemographic factors and utilization of revascularization surgery in moyamoya disease: a systematic review and meta-analysis

Jeremiah Hilkiah Wijaya · Miguel David Quintero Consuegra · Daniela A Perez-Chadid · Aafreen Azmi · y 7 más

Moyamoya disease (MMD) is a rare cerebrovascular disorder in which timely surgical revascularization can prevent stroke. Socioeconomic and sociodemographic factors may influence utilization of revascularization. This systematic review and meta-analysis aimed to quantify associations of household income, insurance type,...

The crossing-sign angle and trochlear dysplasia length: New radiographic parameters to measure the dysplastic trochlea

Juan Pablo Martinez-Cano · Juan Pablo Diaz-Solorzano · Jacobo Triviño-Arias · Andrea Valencia-Orozco · y 2 más

Trochlear dysplasia is one of the most relevant anatomic factors predisposing patients to patellofemoral instability and its recurrence. This study introduces two novel radiographic measurements: the crossing-sign angle and the trochlear dysplasia length.A concordance study was conducted in patients aged 10-40 years wi...

Simulating reentrant mechanisms under structural remodeling: A computational model based on complex-order operators

Juan P. Ugarte · Catalina Tobón

Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia and is strongly associated with electrical and structural remodeling. Fibrosis, a hallmark of structural remodeling, alters myocardial conduction through architectural disruption and electrotonic interactions between cardiomyocytes and fibrobla...

Clinical and biological relevance of objectively-defined subtle cognitive decline in Alzheimer’s disease: a narrative review of neuroimaging, biomarker, and clinical progression studies

Amanda I. Gonzalez · Jairo E. Martinez · Averi Giudicessi · Meredith Rowe · y 5 más

Preclinical Alzheimer's Disease stages represent possible targets for disease-modifying intervention as well as opportunity for early identification of risk for future decline. Recent research has explored the use of objectively-defined subtle cognitive decline (Obj-SCD), an emerging classification that may identify in...

Enhancing the extraction of phenolic compounds from biofortified apple peel by-products: ultrasound-assisted recovery, bioaccessibility, and in vitro bioactivity

Esteban, Villamil-Galindo · Andrea, Piagentini · Alejandro, Gastelúm-Estrada · Cristina, Chuck-Hernandez · y 5 más

This study modeled and optimized ultrasound-assisted extraction (UAE) of phenolic compounds from 'Granny Smith' apple peel (RM) and biofortified peel subjected to controlled abiotic stresses (RM-E). A Box-Behnken design evaluated the effects of extraction ratio, ethanol concentration, and ultrasound power on total phen...

A systematic review: Extended-spectrum beta-lactamase-producing Escherichia coli among cattle, companion animals, synanthropic species, and meat products in South America (2020–2024)

María Isabel García-Álvarez · Stefany Barrientos Villegas · Juana L. Vidal · Luis M. Gómez-Osorio · y 2 más

The spread of ESBL-producing Escherichia coli strains among different hosts, including humans, domestic animals, and synanthropic animals, has become a current public health challenge. A comprehensive analysis of bacterial isolates in animals and meat products throughout South America is essential to improve the unders...