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Colorectal cancer (CRC) remains a global health burden, with rectal cancer comprising approximately one-third of these cases. The standard treatment for locally advanced rectal cancer is neoadjuvant chemoradiotherapy (nCRT) followed by surgery, yet patient responses are highly variable; around 20% achieve a pathologica...
basic medicineNeoadjuvant chemoradiotherapymedical and health sciencesTumour microenvironment
Through the direct and indirect catalysis of redox reactions, microorganisms facilitate the deposition of manganese oxide minerals and drive the global manganese cycle. The overwhelming majority of these organisms are heterotrophic in nature. Thus far, the only species that have demonstrated the ability to chemolithoau...
The importance of organofluorine compounds in disciplines such as agriculture, materials science and medicine has stimulated a long-standing interest among chemists in developing novel synthetic methods to access fluorine-containing molecules. Despite the tremendous success in the construction of C(sp2)–F bonds, the sy...
Nitrogen (N) is an essential nutrient for plant growth and required in relatively high quantities. Plants generally take up N in the form of nitrate and ammonium that are assimilated into amino acids in root plastids or in chloroplasts of mature leaves. Most of the 20 proteinogenic amino acids are produced in the chlor...
Glacier and ice-shelf shear margins are localised zones of intense deformation where flowing ice is in contact with confining valley walls, coastal headlands, or slower-moving ice. Within these zones, ice crystal alignment, grain size, temperature, liquid water content, and brittle damage are modified by and contribute...
The evidence obtained during the last two decades has revealed the crucial role of the gut microbiome in human health. Disruptions in the composition and low diversity of the gut microbial community have been associated with various diseases, including inflammatory bowel conditions, diabetes, cancers and neurological d...
This dissertation argues that in our experience of reading Milton’s poetry, we are confronted with two seemingly opposed ideas: the world is undeniably fallen, and human beings are capable of achieving nearly anything in it. This opposition of fallenness and affirmation manifests in Milton’s art, at crucial moments, as...
languages and literaturehumanities and the artsEnglish Language or Literature
Sign language interpreters who work in video relay services (VRS) routinely face threats to their mental health and well-being. This research study was designed to illuminate the wellness strategies interpreters use to mitigate the psychological and emotional demands of VRS work. The study builds on existing literature...
mental health counselingsign language interpreterCounseling psychologyvideo relay services
The early evolution of basaltic fissure eruptions is often marked by vent localisation, shutdown, migration, and changes in eruption vigour and style, all of which add significant challenges to hazard assessment. These surface dynamics are in part the expression of thermal evolution within the feeder dyke, where heat l...
This thesis investigated how germination impacts the protein quality of oat flour and influences the physicochemical and nutritional properties of an oat beverage across subsequent processing steps. Germination increased protein content by 16%, boosted water-extractable protein by 62%, and elevated free amino groups fi...
agricultural biotechnologyOat protein qualityOat volatilesHigh-pressure homogenisation (HPH)
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ni distribuye estos documentos: cada enlace lleva al repositorio de origen.
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