Buscador de Tesis y publicaciones académicas

Baseline and placebo-related imaging, cerebrospinal fluid, plasma biomarker, and cognitive findings in unimpaired PSEN1 E280A mutation carriers and non-carriers in the Alzheimer’s Prevention Initiative Autosomal Dominant Alzheimer’s Disease Colombia Trial

Tobias Bittner · Francisco Lopera · Silvia Rios-Romenets · Courtney Schiffman · y 34 más

The Alzheimer's Prevention Initiative Autosomal Dominant Alzheimer's Disease (ADAD) Colombia Trial evaluated the biological, cognitive, and clinical effects of crenezumab, an anti-oligomeric and monomeric amyloid-beta (Aβ) monoclonal antibody, in 30-60-year-old PSEN1 E280A mutation carriers without cognitive impairment...

DORSAL: Downlink Optimization for Robust Direct-to-Satellite LoRaWAN

Fraire, Juan · Iova, Oana · Hernandez, Carlos Fernandez · Valois, Fabrice · y 7 más

Delivering downlink ACKs to Class A LoRaWAN devices via LEO satellite constellations requires predicting end-to-end propagation delays of 10–500 ms to hit a 1-second receive window, a timing challenge absent from terrestrial schedulers. We present DORSAL, the first Mixed-Integer Linear Programming (MILP) scheduler for...

Semi-analytical Jeans Filtering Functions for baryonic density and velocity fields in second-order cosmological perturbation theory

Diego Fernando Fonseca · Leonardo Castañeda · Luz Ángela García

Abstract Cosmological perturbation theory provides the fundamental framework for describing the evolution of the matter-energy density field in an expanding Universe and serves as the basis for understanding the formation of large-scale structures within the ΛCDM paradigm. In this work, we present a semi-analytical app...

Comparative Effectiveness and Safety of Unilateral Hemilaminectomy, Unilateral Biportal Endoscopic Decompression, and Percutaneous Transforaminal Endoscopic Surgery for Lumbar Degenerative Disease: A Systematic Review and Meta-Analysis With Pathology-Stratified Exploratory Subgroup Analyses

Juan Fernando Ramón-Cuellar · Fernando Hakim · Diego Gómez-Amarillo · Alexandra Porras-Ramírez · y 5 más

Three minimally invasive lumbar decompression strategies-unilateral hemilaminectomy (UH), unilateral biportal endoscopic decompression (UBE), and percutaneous transforaminal endoscopic surgery (PTES)-are widely used for lumbar degenerative disease, but pathology-stratified comparative evidence remains limited.To compar...

Combined Liver–Kidney Transplantation in Pediatric Patients From Colombia: A Case Series

Alejandro Padilla‐Guzmán · Sergio A. Ortega‐Gamboa · Jessica María Forero‐Delgadillo · Vanessa Amparo Ochoa‐Jiménez · y 5 más

ABSTRACT Background Pediatric combined liver–kidney transplantation is uncommon, and evidence from Latin America is scarce. Methods We report a single‐center case series of four pediatric recipients who underwent combined liver–kidney transplantation at a tertiary Latin‐American center. We summarize primary indications...

CO2-assisted hydrogen recovery from isopropanol over Ni/CeO2 catalysts: Thermodynamic and kinetic insights

Julieth T. García-Sánchez · Alejandro Karelovic · Josefine Schnee · Jean-Marc Krafft · y 4 más

[EN] The difficulties and risks associated with the storage and transport of hydrogen are among the chief challenges for the development of a hydrogen economy. In this context, the use of hydrogen carriers such as the alcohols derived from biomass are deemed promising alternatives to safe storing and transportation. A...

Association of Easier Biologic Access with Remission and Other Clinical Outcomes in Severe Asthma: A Global Real-World Study

Hansen, Susanne · Tsai, Ming-Ju · Tran, Trung · Blakey, John · y 136 más

Time to biologic initiation for the treatment of severe asthma (SA) is affected by many factors, including ease of access to biologics, which is often subject to approval by regulatory authorities and reimbursement criteria by relevant agencies. We investigated the association between ease of biologic access (using the...

Prognostic Factors and Sex-Specific Differences in Neonatal Hypoxic–Ischemic Encephalopathy Treated With Therapeutic Hypothermia

Yaris Anzully Vargas Vaca · Ana María Bertolotto · Esteban Navarro · Mercedes Olaya-C · y 1 más

To identify prognostic determinants of short-term outcomes after neonatal hypoxic-ischemic encephalopathy treated with therapeutic hypothermia, with particular focus on sex-specific differences and the role of perinatal sentinel events.Retrospective cohort study of newborns with hypoxic-ischemic injury treated with the...

Ixekizumab-induced cutaneous vasculitis: A rare challenge in the era of biologic therapies

Benavides Tulcán, Eine Yesid · Vanegas Arciniegas, Sara Isabel · Lozano Ponce, Edgar Andrés

Chorioamnionitis and glucocorticoids elicit acute adverse effects on the developing ovine fetal ovaries

Kay Yi Michelle Seah · Sean William David Carter · Haruo Usuda · Thanapa Rekhawasin Pinnington · y 11 más

Abstract In brief: Preterm birth is frequently associated with antenatal corticosteroid treatment and intrauterine inflammation, yet their effect on fetal ovarian development remain largely unknown. Using a fetal sheep model, we demonstrate that these clinically relevant antenatal exposures induce distinct molecular an...