Buscador de Tesis y publicaciones académicas

Efficacy of saline tract sealing after CT-Guided lung biopsy: a systematic review and meta-analysis

A.T. Kayaoglu · J.M. Almeida · V.V. Varela Betancourt · L.H. Fuenmayor Mena · y 3 más

CT-guided percutaneous transthoracic lung biopsy is a high-value procedure with risks such as pneumothorax and chest tube placement. Several needle-tract sealing techniques have been proposed to reduce post-biopsy pneumothorax, although evidence regarding saline tract sealing remains limited. This study updated a meta-...

Sepsis-induced neuromuscular dysfunction: A systematic review with meta-analysis

Álvaro Becerra · Nicolás Rebolledo · Felipe Soto · Juan José Valenzuela-Fuenzalida · y 5 más

Sepsis-induced neuromuscular dysfunction (SIND) is a common but underrecognized complication in critically ill patients, contributing to prolonged intensive care unit (ICU) stays, increased morbidity, and long-term functional impairment. Its pathophysiology is multifactorial, involving interactions among host factors,...

Artificial Intelligence-informed Architectural Insights of 3-dimensional Glandular Networks Identify Patients With Prostate Cancer at a Higher Risk of Biochemical Recurrence

Jennifer Salguero-Lopez · Sebastian Medina · Robert Serafin · Rui Wang · y 15 más

Pathologists diagnose and grade prostate cancer using thin 2-dimensional (2D) histologic sections, but these 3 to 5 micron sections are too thin to visualize complete glandular networks and 3-dimensional (3D) spatial relationships of adenocarcinomas. We hypothesized that understanding volumetric glandular organization...

Critical model of resilience in children and youth from a Latin American polycrisis context based on a mixed-methods study

Felipe Agudelo-Hernández · Yulissa Mosquera-Cetre · Helena Vélez-Botero

This study proposes a critical resilience model for children and youth in Latin American polycrisis contexts, marked by overlapping adversities including poverty, environmental degradation, armed conflict, and institutional abandonment. In this cross-sectional, sequential mixed-methods study, we combined standardized i...

Post-traumatic Gradenigo syndrome: an uncommoncomplication in the antibiotic era?

Leidy D, Ballén Pinilla · María V, Suárez · Claudia, Quijano

Gradenigo syndrome (GS) is a rare complication of otitis media, secondary to infection spreading to the petrous apex, with potential involvement of cranial nerves V and VI. We present the unusual case of a previously healthy 5-year-old boy who developed GS after a penetrating trauma to the left ear caused by a schoolma...

A continuum of bacterial coexistence equilibrium states sustains mcr-mediated colistin resistance at the human–animal interface

Jhoana P. Romero-Leiton · Yuliana Rodriguez · Carlos Bastidas-Caldes · Liliana Esquivel

Colistin represents one of the last therapeutic options against multidrug-resistant gram-negative bacteria; however, the ecological mechanisms sustaining plasmid-mediated resistance at the human-animal interface remain poorly understood. We develop a deterministic Ordinary Differential Equation model of mcr-mediated re...

Beyond EDSS: Memory-guided saccades as candidate digital biomarkers of processing speed and fatigue in MS—A proof-of-concept study

Mariano Ruiz-Ortiz · Cecilia García-Cena · Rosa Hernández-Ramírez · Andrés Labiano-Fontcuberta · y 4 más

Disability monitoring in multiple sclerosis (MS) relies on EDSS and MRI lesion metrics that are often insensitive to cognitive dysfunction and fatigue.To test whether memory-guided saccade (MGS) performance relates to processing speed and fatigue independent of mood symptoms, EDSS, and MRI inflammatory activity.Forty-f...

The detection of three independent benzimidazole resistance mutations in a single Ancylostoma caninum population from a Golden Retriever breeding kennel in Sao Paulo, Brazil

Mahya Dini · Rebecca Chen · Elizabeth Redman · Christian M. Leutenegger · y 6 más

Multiple anthelmintic drug resistance (MADR) is widespread in the canine hookworm Ancylostoma caninum in kenneled greyhounds in the USA and Australia with benzimidazole resistance being associated with the isotype-1 β-tubulin SNPs Q134H(CAA > CAT) and F167Y(TTC > TAC) in both cases. These two SNPs have also been found...

Latent tuberculosis in rheumatological patients on biologic therapy: methodological considerations and primary care perspective

Juan Sebastián, Therán León · Liliana Cristina, Díaz Cruz · Gustavo Andrés, Díaz Cruz

Comment on: Long-term outcomes of corneal crosslinking for keratoconus across pediatric, adolescent, and adult populations in a diverse U.S. population

Alejandro Tello · José D. Castillo · Manuela Peralta-Olaya · Virgilio Galvis