Buscador de Tesis y publicaciones académicas

The role of mitochondrial calcium transport in neurological diseases

Nguyen, Tam Thi Hong

Mitochondrial Ca2+ uptake and release are crucial for various neuronal processes, including ATP synthesis, synaptic transmission, neurite outgrowth, and gene regulation. However, excessive mitochondrial Ca2+ accumulation can lead to neuronal toxicity via several mechanisms including the opening of the mitochondrial per...

Materials Driven Advancements in Superconducting Nanowire Single Photon Detectors

Patel, Sahil R.

Superconducting Nanowire Single-Photon Detectors (SNSPDs) are the premier single-photon counting technology in the near-infrared regime. Operating via a photon-induced phase transition from the superconducting to the normal state, SNSPDs act as highly sensitive digital detectors that now play a critical role in quantum...

JANE

Arakkal, Alan Tom

While latent space network models have been a popular approach for community detection for over 15 years, major computational and methodological challenges remain. This dissertation introduces novel methodologies to address these limitations, including a fast generalized expectation-maximization algorithm that incorpor...

Too much to be ideal

Jeong, Sujin

Multiple jobholding has become more and more common work arrangement in workplaces nowadays, but it remains unclear how multiple jobholding employees are evaluated at work, especially by their supervisors, who play a significant role in their career advancement. Drawing on the ideal worker norm and lack of fit theory,...

On evaluating medical underwriting in life settlements and mortality table development

Lim, Hong Beng

The life settlement industry is the secondary market for life insurance. The valuation of policies in the life settlement market hinges upon life expectancy assessments provided by medical underwriters. As accurate assessments are essential to the market's well-functioning, determining so is of interest to various stak...

A Dual-Action Mechanism for MAP Kinase Inhibitors

Stadnicki, Emily J

Reversible protein phosphorylation directs essential cellular processes including cell-division, cell-growth, cell-death, inflammation, and differentiation. Because of this, small-molecule-competitive kinase inhibitors have achieved remarkable clinical success, often achieving target specificity by binding to inactive...

A qualitative study utilizing a human factors approach in evaluating the telemedicine user experiences of older adults with visual, hearing, and mobility disabilities

Oche, Onyeche

Methods: This was a qualitative study which used user interviews to obtain data-rich experiences from participants and journey maps to visualize those experiences. User participants had to be at least 60 years old, documented with hearing, mobility, or visual impairment, and must have used telemedicine at least once in...

Energy Sustainability

Evarts, Jonathan S.

To address the control and production of tritium in the fusion fuel cycle, this thesis focuses on: (1) the impact of defects on tritium permeation barriers, and (2) disposal methods for waste streams resulting from tritium production processes. Tritium permeation in a fusion reactor can be reduced by decreasing solubil...

Large-Scale Primary Care Health Precincts: Barriers and Enablers of Integrated Care

Fjaagesund, Shauna

小学生家庭的主题公园动线体验研究 - 以上海迪士尼乐园为例 Researching the route experiences of theme parks of primary school aged children's families - A case study of Shanghai Disneyland

Mei, Yaojiong

主题公园作为重要的休闲和社会文化空间，不仅为游客提供沉浸式的主题环境和多样化的游乐设施，也承载着跨代互动、情感记忆和家庭体验的多重功能。对于小学生亲子家庭而言，主题公园既是娱乐场所，也是观察家庭成员互动与行为模式的重要场景。本研究以上海迪士尼乐园为案例，聚焦小学生家庭的“动线体验”，旨在探索时间因素、团队动态及过程中遭遇...